Effect of L -carnitine on anemia in hemodialysis patients treated with erythropoietin / 第二军医大学学报

Objective:To demonstrate whether L carnitine can further improve the effect of recombinant human erythropoietin (rhEPO) in treatment of anemia. Methods: The patients were randomly divided into 3 groups, group A : L carnitine 1.0 g intravenously infused after every dialysis session; group B: rhEPO 50 150 IU/kg subcutaneously injected once or twice a week; group C: L carnitine and rhEPO given together. The serum albumin, hemoglobin(Hb) and hematocrit(Hct) were monitored for 6 months. Results: The albumin value in L carnitine group was significantly higher than that in rhEPO group ( P